Studies on Local Anesthetics. XVI.
نویسندگان
چکیده
منابع مشابه
Local Anesthetics Properties of Local Anesthetics
The first clinical uses of a local anesthetic agent occurred in 1884, when cocaine was employed as a topical agent for eye surgery and to produce a nerve block. These events inaugurated a new era, that of regional anesthesia. New applications were developed, including spinal, epidural, and caudal anesthesia. The search for a better local anesthetic led to chemical synthesis of a number of other...
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In recent years levobupivacaine, the pure S (-)-enantiomer of bupivacaine, emerged as a safer alternative for regional anesthesia than its racemic parent. It demonstrated less affinity and strength of depressant effects onto myocardial and central nervous vital centers in pharmacodynamic studies, and a superior pharmacokinetic profile. Clinically, levobupivacaine is well tolerated in a variety ...
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Local anesthetics are the most commonly used drugs in dentistry. This article provides a brief update on the pharmacology, adverse effects and clinical applications of these drugs, as well as the role of vasoconstrictors.
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a Istanbul Aydın University, Vocational School of Health Services, Department of Anesthesiology, Istanbul, Turkey b University of Beykent, School of Medicine, Department of General Surgery, Istanbul, Turkey c Karadeniz Technical University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Trabzon, Turkey d Istanbul University, Cerrahpasa Medical Faculty, Department of Histolog...
متن کاملChapter 11 - Local Anesthetics
QUESTIONS OF THE DAY L ocal anesthesia can be defined as loss of sensation in a discrete region of the body caused by disruption of impulse generation or propagation. Local anesthesia can be produced by various chemical and physical means. However, in routine clinical practice, local anesthesia is produced by a narrow class of compounds, and recovery is normally spontaneous, predictable, and co...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1957
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.11-1724